May 2017 Issue of The Translational Scientist

Welcome to the May issue of The Translational Scientist! This month, we take a look at the latest research into the link between immune activation and autism, and interview one of the researchers behind a clinical trial using stem cells to treat stroke. In In Perspective, Marleen Kaatee discusses the importance of listening to patients during medical research. With many more articles coming soon, keep an eye on the website for more of the latest news and views in translational science.

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Articles featured in this issue

Research Field Animal models

Womb with a View

| Roisin McGuigan

Will premature infants soon be able to return to a uterine environment to finish their development?

Research Field Cell & molecular biology

The Extraocular Muscles in ALS: A Research Riddle

| Anton Tjust

Could the preservation of the eye muscles in ALS provide a new outlook on a deadly disease?

Research Field Biomedical engineering

Lab-Grown Bone

| Roisin McGuigan

Engineered biomaterial supports donor blood marrow.

Tools & Techniques Cancer

Cracking Cancer’s Code

| Roisin McGuigan

Sitting Down With George Calin, Professor, The University of Texas MD Anderson Cancer Center, USA.

Research Field Drug discovery

Here Be Dragons

| Rich Whitworth

Antimicrobial peptides found in Komodo dragon plasma provide inspiration for new antibiotics.

Research Field Diagnostics & prognostics

A PCR Technique Out of Left Field

| Joanna Cummings

Using left-handed DNA to better monitor and control PCR.

Research Field Clinical trials

Reuse, Recycle, Regenerate

| Roisin McGuigan

Two repurposed drugs prevent neurodegeneration in mice – and both are already in clinical use.

Tools & Techniques Cell & gene therapy

Small(er) Sequence, Big(ger) Promise

| Ruth Steer

CRISPR gene editing with a newly characterized orthologue may bring the approach closer to the clinic.

Tools & Techniques Cancer

A Winning Combination?

| Roisin McGuigan

Engineering more effective antibody-drug conjugates.

Research Field Immunology

Immune Activation and Autism

| William Aryitey

A genetic pathway behind autism spectrum disorder may have been uncovered

Research Field Cell & gene therapy

Stem Cells for Stroke Recovery

| William Aryitey

A phase II trial shows the safety and efficacy of progenitor cells in stroke victims

Research Field Clinical trials

The Missing Piece of the Puzzle

| Marleen Kaatee

Marleen Kaatee explores how patients' voices can be important in medical research

Other issues of 2017