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Outside the Lab Policy

Moving on from the Great CRISPR Controversy

| Jonathan James

How will the storm whipped up by He Juinkai’s flagrant disregard for medical ethics affect the wider ambitions of the gene-editing field?

Research Field Cell & gene therapy

Now For the High-Hanging Fruit

| Miguel Forte

We should be thrilled with the success of the approved CD-19 CAR-T therapies. But the field is still young, and we are only scratching the surface of what’s possible.

Tools & Techniques Cancer

Cytotoxic Remediation

| Jonathan James

How a 3D-printed chemical absorber could pave the way for higher chemotherapy doses – or lower risks.

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Latest Articles

Tools & Techniques Informatics

RePURPOSED

| Maryam Mahdi

Recycled and reused: scientists develop a library to help teach old drugs new tricks.

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Disease Area Cancer

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

Disease Area Neurological

Alzheimer's Awakening

| Jonathan James

Changes in non-REM sleep may indicate early AD

Disease Area Cancer

No-Biotics for Me!

| Gemma North

We don’t fully understand how probiotics affect cancer patient prognosis, so they should be approached with caution – at least for now.

Tools & Techniques Imaging

FDISCO

| Jonathan James

A new tool in the pathologist’s arsenal may allow 3D imaging of tissues and organs.

Tools & Techniques Diagnostics & prognostics

IAs - ID'd

| Jonathan James

How the RNA transcriptome of circulating neutrophils could hold the key to identifying intracranial aneurysms – before they rupture.

Disease Area Infectious diseases

Managing Malaria with Smarter Sampling

| Jonathan James

How targeting subclinical populations with a rapid saliva test may aid in the quest to eradicate the disease.

Disease Area Neuroscience

Holding Back the Years

| Maryam Mahdi

Seeking inspiration from plants in the fight against Alzheimer’s disease.

Research Field Gene Editing

Dinner with a CRISPR Connoisseur

| Jonathan James

Harvard Medical School’s Richard Sherwood digs into the potential and pitfalls of gene editing technology.

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