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Animal models

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Research Field Animal models

Skin in the Game

| William Aryitey

Could donated human skin provide a viable alternative to animal testing?

Tools & Techniques Drug discovery

Escaping the Rat Race

| Stefan Amisten

Over-reliance on rodent models could be leading drug discovery in the wrong direction

Tools & Techniques Cancer

Rush at Your Peril

| Eleftherios P. Diamandis

False discoveries have plagued biomarker research for years: don't trust everything you read.

Outside the Lab Animal models

Pulling Back the Pre-Clinical Curtain

| William Aryitey

Are mouse models the best option we have?

Research Field Animal models

Womb with a View

| Roisin McGuigan

Will premature infants soon be able to return to a uterine environment to finish their development?

Tools & Techniques Cell & gene therapy

Small(er) Sequence, Big(ger) Promise

| Ruth Steer

CRISPR gene editing with a newly characterized orthologue may bring the approach closer to the clinic.

Tools & Techniques Animal models

An End to Animal Testing is Not Yet in Sight

| Sandy Mackay, Bella Williams

We need alternatives but, right now, in vivo methods might be the best option we have

Tools & Techniques Imaging

Amazing Animals (The Art of Translation)

Incredible images of the animal models that play such a vital role in medical research

Tools & Techniques Drug discovery

When is a Negative a Positive?

| Robert S. Kerbel

We need to change attitudes towards publishing "negative" results


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