Animal models

Tools & Techniques Clinical trials

A Translation Boost for USH

| Sarah Healey | 4 min read

Improving translational models for inherited retinal diseases

Research Field Drug discovery

A Model Experiment

| Audrey Dubourg

Harnessing the potential of microphysiological systems to advance drug discovery.

Research Field Biomedical engineering

Corneal Construction

| Jonathan James

Researchers fine-tune 3D printing technology to create better biomimetic corneas – and predict a “breakthrough” in global transplantation practice.

Disease Area Metabolism & Diabetes

Tackling the Fatty-Liver Timebomb

| Jonathan James

Could modulation of fibroblast growth factor 21 translate into a new treatment for non-alcoholic fatty liver disease?

Research Field Animal models

Going out on a (Regrown) Limb

| Jonathan James

Meet the researchers uncovering the secrets of tissue regeneration.

Research Field Cancer

Cancer and the Microbiome

| Ivan Gladwyn-Ng, Alexander Maue

How advanced studies into the microorganisms we harbor could impact cancer prevention, treatment, and prognosis.

Disease Area Cancer

Two-pronged Attack on Neuroblastoma

| Jonathan James

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Research Field Animal models

Skin in the Game

| William Aryitey

Could donated human skin provide a viable alternative to animal testing?

Tools & Techniques Drug discovery

Escaping the Rat Race

| Stefan Amisten

Over-reliance on rodent models could be leading drug discovery in the wrong direction


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