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Disease Area Cancer, Animal models, Drug discovery

Two-pronged Attack on Neuroblastoma

The MYCN oncogene – highly upregulated in neuroblastoma – has long been regarded as an attractive target for therapy, but successful translation into the clinic has proven challenging (1). Attention thus turned to downstream pathways and, now, a multinational team of researchers has demonstrated the feasibility of targeting two aspects of a crucial pathway in cancer growth: polyamine synthesis and uptake (2).

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About the Author

Jonathan James

As an assistant editor for The Translational Scientist, I can combine two of my passions; translational science research and science communication. Having thrown myself into various editing and other science communication gigs whilst at University I came to realise the importance of good quality content that delivers in an exciting and engaging way.

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