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Disease Area


Disease Area Cancer

Proving the worth of ICIs

| Jonathan James

New evidence points to the safety – and benefits – of immune checkpoint therapy in HIV-positive cancer patients

Disease Area Neurological

Neurons Under (Astroctyic) Attack

| Jonathan James

Could manipulation of micro-RNA cross-talk between astrocytes and neuronal cells yield a new therapeutic avenue for ALS?

Disease Area Cancer

Two-pronged Attack on Neuroblastoma

| Jonathan James

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.

Disease Area Metabolism & Diabetes

Bite-size Breakthroughs: IELS, Imaging and Ocular Cancer

| Jonathan James

The latest advances in translational medicine – condensed into 20-second servings.

Disease Area Cancer

Gurus of Brain Oncology

| Jonathan James

Three leading lights in the neuro-oncology sphere explain what inspired them, how the field has evolved, and what challenges lie ahead.

Disease Area Cancer

Adaptive Invaders

| Jonathan James

New evidence suggests there’s more to metastasis than MMPs, demanding a therapeutic rethink.

Disease Area Metabolism & Diabetes

Grappling GK

| Jonathan James

How a new compound promises to selectively activate hepatic glucokinase in a bid to treat type 2 diabetes.

Disease Area Neurological

Breakdown Breakthrough

| Jonathan James

Exploring the link between blood brain barrier permeability and cognitive dysfunction.

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Disease Area Cancer

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

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