Disease Area

Could modulation of fibroblast growth factor 21 translate into a new treatment for non-alcoholic fatty liver disease?

Combining metabolomics and DNA sequencing could be the key to discovering new inborn errors of metabolism in children.

How sex-dependent differences in molecular mechanisms could underpin men and women’s distinct experiences of chronic neuropathic pain.

New evidence points to the safety – and benefits – of immune checkpoint therapy in HIV-positive cancer patients

Could manipulation of micro-RNA cross-talk between astrocytes and neuronal cells yield a new therapeutic avenue for ALS?

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.

The latest advances in translational medicine – condensed into 20-second servings.

Three leading lights in the neuro-oncology sphere explain what inspired them, how the field has evolved, and what challenges lie ahead.

New evidence suggests there’s more to metastasis than MMPs, demanding a therapeutic rethink.

How a new compound promises to selectively activate hepatic glucokinase in a bid to treat type 2 diabetes.