Disease Area Omics, Analytical science, Cancer

Monitoring Kinome Adaptations to Therapy using Quantitative High Resolution Mass Spectrometry

sponsored by Thermo Fisher Scientific

June 23, 2016 8:00 AM PDT 11:00 AM EST

Register Free

Historically, researchers have utilized technologies such as qRT-PCR, Taqman Gene expression assays, western blotting, and liquid chromatography mass spectrometry that allow them to look at single kinases in a relatively linear fashion. Learn how studying the kinome as a whole entity, using additional technologies like quantitative high resolution orbital mass spectrometry, can aide in understanding how tumors may evade current therapies by altering their kinome state. Using this information, learn how clinical translational researchers are investigating new and potentially more effective kinase inhibitor combination therapies for complex diseases like cancer.

Key Learning Objectives:

What you will learn:

  • Define methods to study protein kinome “en masse” using chemical proteomics.
  • Identify novel kinase inhibitor combinations that overcome drug resistance.
  • Explore the function of protein kinases that represent the (un) targeted kinome.
Hosted by

Charlotte Barker, Editor,

The Translational Scientist

James S. Duncan, PhD

Assistant Professor, Fox Chase

Cancer Center at Temple Health

Sponsored by

Register Free

Receive content, products, events as well as relevant industry updates from The Translational Scientist and its sponsors.

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

Related Solutions
Powering Proteomics: E-book

| Contributed by SomaLogic

Precision medicine and large-scale plasma protein profiling

| Contributed by Thermo Fisher Scientific

Tools & Techniques Imaging
Raman Analysis of Pharmaceutical Ingredients

| Contributed by Ocean Optics

Register to The Translational Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts