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Cell & gene therapy

Research Field Cell & gene therapy

Buried Treasure

| William Aryitey

Previously thought to be "junk", long noncoding RNAs may play a central role in cancer

Tools & Techniques Cancer

Video: Inside The Translational Scientist

| Charlotte Barker

Want a lightning-fast tour of the latest issue? Take a look at our new video sneak preview.

Tools & Techniques Cancer

Immune U-Turn

| Charlotte Barker

“Extraordinary” results from a T-cell therapy trial offer hope to leukemia patients – and to researchers toiling in unfashionable fields.

Tools & Techniques Cell & gene therapy

Stemming the Flow

| Paris Margaritis

A gene therapy approach for hemophilia-causing Factor VII deficiency shows early promise

Research Field Cardiovascular

State-of-the-Heart Tissue Models

| John Ahrens and Joseph C. Wu

A decade after Shinya Yamanaka brought us induced pluripotent stem cells, our ability to generate an endless supply of human heart cells is being put to good use in research and development.

Tools & Techniques Cancer

Building a Better Mousetrap

| Michael Schubert

It’s often difficult to target pancreatic cancer cells while sparing healthy tissue – but a new therapy concept not only makes this possible, but also enhances the potential effectiveness of adjuvant treatments

Tools & Techniques Cancer

An Epigenetic Epiphany

| Michael Schubert

When genetics yielded unsatisfactory answers about pancreatic cancer’s persistent survival, researchers looked beyond the genome – and found telling epigenetic changes

Tools & Techniques Cancer

Breaching Cancer’s Defenses

| Ingunn Stromnes

A new immunotherapy approach shows that engineered T cells are able to penetrate into pancreatic tumors and directly attack the cancer

Tools & Techniques Cancer

(Chemo)resistance Is Futile

| Michael Schubert

The epithelial-to-mesenchymal transition in pancreatic cancer may play a role in its resistance to treatment – and inhibiting it may improve treatment efficacy

Tools & Techniques Cell & gene therapy

Mission: Impossible

| Michael Schubert

Pancreatic cancer is tough to understand, diagnose and treat. Undeterred researchers are on a quest to crack the case.


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