Noncoding DNA makes up the majority of our genomes, much of it being conserved and transcribed. Though the functions of small regulatory RNA molecules are well known, what about so-called long non-coding RNA? Pioneering scientists are digging up secrets hidden in the labyrinthine depths of our chromosomes.
William Aryitey |
Genomic explorations have offered us a great deal of insight into the complexities and intricacies of life. But for all the knowledge we’ve gained, there is still much we do not understand when we step outside the central dogma of “DNA to RNA to protein”. Take non-protein coding transcripts of over 200 nucleotides as a prime example. Previously thought to be “junk” genetic elements, new functions and classes of long non-coding RNAs (lncRNAs) are rapidly emerging.
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