Tools & Techniques

Advances in mass spectrometry and separation science are bringing genome-scale proteomic analyses within our reach.

Anthony Quinn shares the story behind the development and approval of sebelipase alfa (Kanuma) – the first and only enzyme replacement therapy for lysosomal acid lipase deficiency (LAL-D).

To select the right treatment for each cancer patient, we need fast, accurate and cost-effective ways to characterize tumors. Now, with newly developed algorithms and protocols, mate pair sequencing could well be the tool we’ve been seeking.

Pharma companies are notoriously protective of their intellectual property, so it’s a big deal to open up and give knowledge away for free.

We’ve come a long, long way already. Where next for NGS?

Drug discovery doesn’t always begin in the lab…

Identifying babies at risk of deadly gastrointestinal disease through microbiomics

Want a lightning-fast tour of the latest issue? Take a look at our new video sneak preview.

“Extraordinary” results from a T-cell therapy trial offer hope to leukemia patients – and to researchers toiling in unfashionable fields.

As the judges deliberate over this year's winner, we speak with three of the top-placed entrants from the 2015 Humanity in Science Award.