Tools & Techniques

Tools & Techniques Diagnostics & prognostics

Viruses Face the Ultimate Test

| William Aryitey

Shotgun sequencing is a powerful tool in microbial genomics, but viral genomes have proven tough to crack.

Tools & Techniques Cell & gene therapy

Stemming the Flow

| Paris Margaritis

A gene therapy approach for hemophilia-causing Factor VII deficiency shows early promise

Tools & Techniques Cell & molecular biology

Cellular Night Vision

| William Aryitey

French physicists have developed a thermal imaging technique that maps heat across a single cell

Tools & Techniques Cancer

Building a Better Mousetrap

| Michael Schubert

It’s often difficult to target pancreatic cancer cells while sparing healthy tissue – but a new therapy concept not only makes this possible, but also enhances the potential effectiveness of adjuvant treatments

Tools & Techniques Cancer

An Epigenetic Epiphany

| Michael Schubert

When genetics yielded unsatisfactory answers about pancreatic cancer’s persistent survival, researchers looked beyond the genome – and found telling epigenetic changes

Tools & Techniques Cancer

Breaching Cancer’s Defenses

| Ingunn Stromnes

A new immunotherapy approach shows that engineered T cells are able to penetrate into pancreatic tumors and directly attack the cancer

Tools & Techniques Cancer

(Chemo)resistance Is Futile

| Michael Schubert

The epithelial-to-mesenchymal transition in pancreatic cancer may play a role in its resistance to treatment – and inhibiting it may improve treatment efficacy

Tools & Techniques Cell & gene therapy

Mission: Impossible

| Michael Schubert

Pancreatic cancer is tough to understand, diagnose and treat. Undeterred researchers are on a quest to crack the case.

Tools & Techniques Public health

Benefits of a Drug You Never Use

| Nicholas W. Papageorge

Raising awareness of the hidden beneficiaries of medical innovation could help boost funding for drug development.

Tools & Techniques Genetics

Catching the Thermodynamic Express

| David Zhang

A new method could dramatically speed up analysis of nucleic acid thermal behavior

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