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Research Field Cell & molecular biology

Missed Connections

| William Aryitey

A protein critical for synaptic plasticity in baby mice could hold clues to the origins of autism

Research Field Cancer

Decoding Cancer Cross-Talk

| William Aryitey

Intercepting communication between cancer cells and endothelium uncovers clues to metastasis mechanisms

Research Field Cancer

Chemotherapy All Wrapped Up

| William Aryitey

Could exosome encapsulation be the secret to delivering higher potency in chemotherapy?

Disease Area Public health

Only Half the Battle

| Charlotte Barker

The true mission of translational science is to take new medicines and diagnostics from bench to bedside – and beyond

Tools & Techniques Cell & gene therapy

Image of the Month

| Charlotte Barker

Researchers at MIT have programmed induced pluripotent stem cells to form rudimentary livers, complete with different tissues, by engineering expression of GATA6.

Research Field Neuroscience

Video: Inside The Translational Scientist

| Charlotte Barker

Want a lightning-fast tour of the latest issue? Take a look at our new video sneak preview.

Research Field Neuroscience

Bargain Brains

| Diane Hoffman-Kim

In some ways, we biomedical engineers are really just control freaks. By designing our own small world in a dish, we can stage manage every aspect and push the boundaries in a way that’s not always possible in an animal model.

Disease Area Biomedical engineering

Enter the Matrix

| Cathy Merry

Now I have a lab of my own, I’ve found that the best research comes from finding the right collaborators.

Research Field Animal models

Animal Alternatives

| James Strachan, Charlotte Barker

Could the lab rat be heading for retirement? A new breed of in vitro tissues and organs are being engineered to replace animal models – and the developers aim to make them accessible to all.

Outside the Lab Cancer

Oncotherapy Goes Viral

| Robert Coffin

Robert Coffin tells the bench-to-bedside story of how the first FDA-approved oncolytic virotherapy, talimogene laherparepvec (T-VEC), was translated from a colleague’s cold sore to a potential global game changer.

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