Tools & Techniques Cell & gene therapy, Imaging

Image of the Month

Credit: Patrick Guye and colleagues, MIT.

Researchers at MIT have programmed induced pluripotent stem cells to form rudimentary livers, complete with different tissues, by engineering expression of GATA6. The scientists foresee potential for drug screening, and eventually maybe even replacement organs. The image shows the tissue patterns formed, with immunostaining of cell nuclei for CEBPA (red, endodermal marker), SOX10 (green, ectodermal marker), and DAPI (blue, binds to DNA in the nucleus).

Read more about engineered tissues for research and drug development here.

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Charlotte Barker

“As Editor of The Translational Scientist, I’m working closely with our audience to create vibrant, engaging content that reflects the hard work and passion that goes into bringing new medicines to market. I got my start in biomedical publishing as a commissioning editor for healthcare journals and have spent my career covering everything from early-stage research to clinical medicine, so I know my way around. And I can’t think of a more interesting, challenging or important area to be working in.”

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