Drug discovery

A breakthrough in transgenic mice opens the door to “Humabodies.”

AstraZeneca's George Kirk tells us the story of Koselugo – a treatment for the rare genetic condition neurofibromatosis 1.

How can we encourage companies to pursue clinical research for CNS disorders?

Harnessing the potential of microphysiological systems to advance drug discovery.

Small-molecule inhibition of the SARS-CoV-2 viral protease may represent a promising route for therapy

The drug development system is broken; the COVID-19 pandemic is an opportunity to take a bold step towards accessible and affordable therapies

Expert pathologist Fred Plapp offers a summary of the virus causing COVID-19, its effects, and the pandemic’s evolving status

How advanced studies into the microorganisms we harbor could impact cancer prevention, treatment, and prognosis.

A chemical cocktail of small molecules shows promise in driving neuro-regeneration.

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.