Cancer

Tools & Techniques Cancer

Breaching Cancer’s Defenses

| Ingunn Stromnes

A new immunotherapy approach shows that engineered T cells are able to penetrate into pancreatic tumors and directly attack the cancer

Tools & Techniques Cancer

(Chemo)resistance Is Futile

| Michael Schubert

The epithelial-to-mesenchymal transition in pancreatic cancer may play a role in its resistance to treatment – and inhibiting it may improve treatment efficacy

Tools & Techniques Cell & gene therapy

Mission: Impossible

| Michael Schubert

Pancreatic cancer is tough to understand, diagnose and treat. Undeterred researchers are on a quest to crack the case.

Research Field Cancer

No Biomarker, No Trial?

| James Ritchie, Sidath Katugampola, Paul Jones

The vast majority of experimental cancer drugs fail during the later stages of clinical development

Tools & Techniques Cancer

PD-1 on the Brain

| William Aryitey

Revolutionary cancer immunotherapies appear to alleviate Alzheimer’s symptoms in mice

Research Field Cancer

Decoding Cancer Cross-Talk

| William Aryitey

Intercepting communication between cancer cells and endothelium uncovers clues to metastasis mechanisms

Research Field Cancer

Chemotherapy All Wrapped Up

| William Aryitey

Could exosome encapsulation be the secret to delivering higher potency in chemotherapy?

Disease Area Biomedical engineering

Enter the Matrix

| Cathy Merry

Now I have a lab of my own, I’ve found that the best research comes from finding the right collaborators.

Outside the Lab Cancer

Oncotherapy Goes Viral

| Robert Coffin

Robert Coffin tells the bench-to-bedside story of how the first FDA-approved oncolytic virotherapy, talimogene laherparepvec (T-VEC), was translated from a colleague’s cold sore to a potential global game changer.

Research Field Cancer

Personalized Medicine × Nanotechnology

| Tamara Minko

The combination of genomic profiling and high-tech targeted drug delivery is opening up a new front in the fight against cancer.

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