Cancer

Retrotransposons can initiate oncogenesis, with an increased risk in certain populations

A novel PDX screening technique has uncovered new molecular drivers for PDAC

Pancreatic cancer cells don’t seem to rely on EMT for metastasis – but it plays a key role in their ability to resist our best chemotherapy options

A triple-transgenic mouse model allows researchers to trace the lineage of EMT tumor cells, and reveals the transition’s surprising lack of significance in metastasis

Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind the limitations.

Sitting Down With… Robert A. Weinberg, founding member of the Whitehead Institute for Biomedical Research and Professor of Biology at the Massachusetts Institute of Technology, USA.

As cancer rates continue to climb, low and middle income countries are ramping up prevention and screening efforts.

What does it take to create a competitive companion diagnostic? Bharathi Vennapusa outlines her role in the development and approval of the ALK CDx – a fully-automated immunohistochemistry assay that identifies lung cancer patients who may be eligible for treatment with Pfizer’s Xalkori (crizotinib).

Long thought to be a key component of the metastatic process, researchers are now questioning long-held beliefs on the role of the epithelial-to-mesenchymal transition.

Are the metrics used to measure cancer drug efficacy inherently flawed?