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Diagnostics & prognostics

Disease Area Cancer

In Good Company

| Bharathi Vennapusa

What does it take to create a competitive companion diagnostic? Bharathi Vennapusa outlines her role in the development and approval of the ALK CDx – a fully-automated immunohistochemistry assay that identifies lung cancer patients who may be eligible for treatment with Pfizer’s Xalkori (crizotinib).

Tools & Techniques Cancer

Cells on the (Invasion) Front Lines

| Michael Schubert

Long thought to be a key component of the metastatic process, researchers are now questioning long-held beliefs on the role of the epithelial-to-mesenchymal transition.

Tools & Techniques Public health

On the Spot Diagnosis

| Laura Lechuga

Mobile devices promise a new future of point-of-care diagnostics for all

Tools & Techniques Omics

Clinical Translation Through Innovation

| Thomas Conrads

Advances in mass spectrometry and separation science are bringing genome-scale proteomic analyses within our reach.

Tools & Techniques Omics

Disrupting Cytogenetics in the Clinic

| George Vasmatzis

To select the right treatment for each cancer patient, we need fast, accurate and cost-effective ways to characterize tumors. Now, with newly developed algorithms and protocols, mate pair sequencing could well be the tool we’ve been seeking.

Tools & Techniques Drug discovery

A Story of Shared Science and Solutions

| Niclas Nilsson

Pharma companies are notoriously protective of their intellectual property, so it’s a big deal to open up and give knowledge away for free.

Tools & Techniques Diagnostics & prognostics

Baby Biomarkers

| William Aryitey

Identifying babies at risk of deadly gastrointestinal disease through microbiomics

Tools & Techniques Diagnostics & prognostics

Analyzing Humanity

| Joanna Cummings

As the judges deliberate over this year's winner, we speak with three of the top-placed entrants from the 2015 Humanity in Science Award.

Tools & Techniques Diagnostics & prognostics

Viruses Face the Ultimate Test

| William Aryitey

Shotgun sequencing is a powerful tool in microbial genomics, but viral genomes have proven tough to crack.

Tools & Techniques Cancer

Building a Better Mousetrap

| Michael Schubert

It’s often difficult to target pancreatic cancer cells while sparing healthy tissue – but a new therapy concept not only makes this possible, but also enhances the potential effectiveness of adjuvant treatments

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