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Research Field Genetics

The Impact of COMET

| Ralph Mazitschek, Stephen J. Haggarty

COMET could allow precise spatiotemporal targeting of disease-controlling mechanisms

Research Field Cancer

Retrotransposon Risks

| William Aryitey

Retrotransposons can initiate oncogenesis, with an increased risk in certain populations

Research Field Biomedical engineering

Building the Human Genome

| William Aryitey

An ambitious, large-scale project plans to fully construct a synthetic human genome

Research Field Genetics

A Genetic Basis for MS

| William Aryitey

The discovery of multiple sclerosis' genetic origin may lead to better therapies

Research Field Genetics

Ghost in the Cell

| William Aryitey

New software couples computer programming with cell function using the ultimate coding language: DNA

Research Field Drug discovery

Arresting ALS

| Joe Beckman

When it comes to prognosis, the mouse models I use to study amyotrophic lateral sclerosis (ALS) are sadly accurate – like their human counterparts with familial ALS, all mice with these mutations die young. After 20 years of trying – and failing – to find a treatment that could extend life, I was close to giving up, until a new drug candidate came along. Then something amazing happened – a mouse lived.

Outside the Lab Genetics

Gene Genie

| John Doench

Sitting Down With…John Doench, Associate Director, Genetic Perturbation Platform, Broad Institute, Cambridge, MA, USA.

Research Field Cardiovascular

One Man’s Trash…

| William Aryitey

Researchers dive through genetic “junk” to discover a small protein with lots of heart

Tools & Techniques Genetics

Catching the Thermodynamic Express

| David Zhang

A new method could dramatically speed up analysis of nucleic acid thermal behavior

Tools & Techniques Genetics

CRISPR Controversy

| David Baltimore, Jonathan Moreno, John Harris, David Lemberg

CRISPR has brought gene editing into the mainstream – but where should we draw the line?

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