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Cancer

Disease Area Cancer

Two-pronged Attack on Neuroblastoma

| Jonathan James

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.

Tools & Techniques Drug delivery

Heavy Metal Wonder

| Jonathan James

An iridium-based photodynamic drug accumulates in cancer cell nuclei – and destroys them from within.

Research Field Microbiology

Monitoring the Microbiome

| Luke Turner

Differences in bacterial diversity in the gut could be used to identify patients with Barrett’s esophagus and esophageal cancer.

Tools & Techniques Cancer

The Story and Science Behind the "Mini-brain"

| Simon Plummer

How iPSC-derived 3D organoids and high-throughput histology opens a new door to personalized medicine development and testing.

Disease Area Metabolism & Diabetes

Bite-size Breakthroughs: IELS, Imaging and Ocular Cancer

| Jonathan James

The latest advances in translational medicine – condensed into 20-second servings.

Disease Area Cancer

Gurus of Brain Oncology

| Jonathan James

Three leading lights in the neuro-oncology sphere explain what inspired them, how the field has evolved, and what challenges lie ahead.

Disease Area Cancer

Adaptive Invaders

| Jonathan James

New evidence suggests there’s more to metastasis than MMPs, demanding a therapeutic rethink.

Research Field Cell & gene therapy

Now For the High-Hanging Fruit

| Miguel Forte

We should be thrilled with the success of the approved CD-19 CAR-T therapies. But the field is still young, and we are only scratching the surface.

Disease Area Cancer

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

Disease Area Cancer

No-Biotics for Me!

| Gemma North

We don’t fully understand how probiotics affect cancer patient prognosis, so they should be approached with caution – at least for now.

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