Monitoring the Microbiome
Can gut microbiota help improve the diagnosis and management of esophageal cancer?
Luke Turner |
Esophageal cancer is the sixth most common cause of cancer-related death worldwide despite the introduction of innovative surgical, chemotherapeutic, and radiological interventions. The high mortality rate is largely attributed to the large number of patients presenting with established disease, signaling a need for improved diagnostic tools to accurately dissect individual risk. To improve the odds, a research group led by Loris Lopetuso from Catholic University of Rome, Italy, delved into the pathogenesis of esophageal adenocarcinoma (EAC), asking: what drives the transition from normal esophageal epithelium to Barrett’s esophagus (BE) and EAC? And can we detect a unique signature that might allow us to spot the changes early (1)?
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