Research Field Public health

Stimulating Regulatory Science

| Jan Johannessen, Ameeta Parekh

We need better tools for assessing new medicines – and to develop them, we must work together.

Outside the Lab Professional development

Collaborate or Die

| Richard Holland

In the pharma industry of the future, only the strongest companies will survive – and that means those with the most successful collaborations.

Research Field Metabolism & Diabetes

A Single-Edged Sword for Diabetes?

| James Strachan

Autocrine-based screening has identified a more selective anti-diabetic drug candidate

Tools & Techniques Genetics

CRISPR Controversy

| David Baltimore, Jonathan Moreno, John Harris, David Lemberg

CRISPR has brought gene editing into the mainstream – but where should we draw the line?

Outside the Lab Cancer

Does Screening Save Lives?

| Ian Jacobs

Data from a large-scale trial suggest that screening cuts ovarian cancer mortality rates by 25 percent – but some remain skeptical

Tools & Techniques Biomedical engineering

Cellular Prostheses for Psoriasis

| James Strachan

Could cell-based synthetic circuits make pills and ointments a thing of the past for chronic disease?

Tools & Techniques Drug delivery

The Overactive Brain

| Michela Gallagher

Michela Gallagher was studying aging in lab rats when an unusual finding launched her on a translational journey that now sees her poised to initiate a Phase III trial of a drug to delay the onset of Alzheimer’s dementia.

Research Field Neuroscience

Untangling Tau

| Bradley Hyman

As a neurologist, Bradley Hyman has seen first-hand the impact of Alzheimer’s disease on patients and their families.

Research Field Neuroscience

Navigating Alzheimer’s

| Charlotte Barker

Our understanding of the mechanisms that trigger Alzheimer’s disease is growing fast, but many secrets still lurk in the shadowy recesses of the brain.

Disease Area Personalized medicine

Making It (Im)personal

| Julian Solway

Better understanding of human biology presents us with an opportunity to combat disease on two fronts – targeting individual variation on one hand and universal mechanisms on the other.

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