How and what we measure in animal studies of pain has huge implications for clinical translation.

Does pain in early childhood have a profound impact later in life?

Chronic pain is the most prevalent and expensive public health problem in the developed world, but as a society we consistently fail to recognize the scale of the public health issue.

Basic and clinical researchers must join forces to fight pain.

Hundreds of potential drug targets have been discovered by researchers mapping pain pathways, but clinical trials have proved unsuccessful in most cases. Can we pick our way through the translational maze to find much-needed new analgesics?

Sitting Down With…John Doench, Associate Director, Genetic Perturbation Platform, Broad Institute, Cambridge, MA, USA.

The Ebola epidemic spurred a tremendous amount of R&D in search of vaccines and treatments – and yet it was a relatively low impact global emergency compared with malaria.

There is an assumption that doctors and business don’t mix. But I believe physicians are ideally placed to bring new clinical innovations from a bright idea to a brand new product.

Open innovation is more than just the latest pharma industry buzzword. Done right, it can help overcome funding challenges and accelerate discovery across the board.

A gene therapy approach for hemophilia-causing Factor VII deficiency shows early promise