Content by Charlotte Barker:

Research Field Analytical science

The Shape of Proteins to Come

| Charlotte Barker

A new technique allows scientists to see conformational changes caused by ligand binding in real time, opening up new screening options for drug discovery.

Disease Area Pain & critical care

The Problem With Pain

| Charlotte Barker

Hundreds of potential drug targets have been discovered by researchers mapping pain pathways, but clinical trials have proved unsuccessful in most cases. Can we pick our way through the translational maze to find much-needed new analgesics?

Disease Area Immunology

Image of the Month

| Charlotte Barker

On each side of the brain stem, a florescent green marker illuminates the two networks of 200 neurons that control the sighing reflex

Outside the Lab Infectious diseases

Video: Inside The Translational Scientist

| Charlotte Barker

Want a lightning-fast tour of the latest issue? Take a look at our new video sneak preview.

Disease Area Public health

Only Half the Battle

| Charlotte Barker

The true mission of translational science is to take new medicines and diagnostics from bench to bedside – and beyond

Tools & Techniques Cell & gene therapy

Image of the Month

| Charlotte Barker

Researchers at MIT have programmed induced pluripotent stem cells to form rudimentary livers, complete with different tissues, by engineering expression of GATA6.

Research Field Neuroscience

Video: Inside The Translational Scientist

| Charlotte Barker

Want a lightning-fast tour of the latest issue? Take a look at our new video sneak preview.

Research Field Animal models

Animal Alternatives

| James Strachan, Charlotte Barker

Could the lab rat be heading for retirement? A new breed of in vitro tissues and organs are being engineered to replace animal models – and the developers aim to make them accessible to all.

Outside the Lab Cancer

Perfecting the Translational Balancing Act

| Charlotte Barker

Sitting Down With… Jennifer Grandis, Professor, Department of Otolaryngology – Head and Neck Surgery, Associate Vice Chancellor – Clinical and Translational Research, University of California, San Francisco, USA.

Research Field Neuroscience

Navigating Alzheimer’s

| Charlotte Barker

Our understanding of the mechanisms that trigger Alzheimer’s disease is growing fast, but many secrets still lurk in the shadowy recesses of the brain.

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