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Anthony Quinn shares the story behind the development and approval of sebelipase alfa (Kanuma) – the first and only enzyme replacement therapy for lysosomal acid lipase deficiency (LAL-D).

From being one of the first clinicians to voice doubts over Vioxx, to his latest book calling for a complete transformation of the patient–doctor relationship, Eric Topol has never been afraid to raise his head above the parapet.

To select the right treatment for each cancer patient, we need fast, accurate and cost-effective ways to characterize tumors. Now, with newly developed algorithms and protocols, mate pair sequencing could well be the tool we’ve been seeking.

Sitting Down With… Thomas Mellman, Professor and Director, Center for Clinical and Translational Research and Stress/Sleep Studies Program, Howard University College of Medicine, Washington, DC, USA.

The moment a baby enters the world – even before its first breath – the tiny body receives a massive infusion of bacteria, viruses and fungi.

We’ve come a long, long way already. Where next for NGS?

The pharmaceutical industry receives its fair share of both praise and scorn. Behind the politics, the hard work and impressive achievements of legions of industry researchers often go unnoticed.

Mimiviruses don’t really fit into any known group of living things – let’s be brave and come up with a new domain, lest we stifle progress.

Understanding how blood vessels calcify could help prevent cardiovascular disease

A new type of dressing can promote healing and fight off infection in burn wounds