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Disease Area Analytical science, Diagnostics & prognostics, Personalized medicine, Metabolism & Diabetes

The Biomarker Breakdown

It’s a classic “chicken and egg” scenario. When retinal diseases like age-related macular degeneration (AMD) strike, early diagnosis and intervention give the best prognosis and visual outcomes. But in reality, retinal disease cannot be diagnosed until structural changes are seen, and some patients only present at ophthalmology clinics when the visual symptoms – and the underlying pathology – are at an advanced stage. Now, a team from Massachusetts Eye and Ear Hospital, Boston, USA, are proposing that metabolomics analysis might hold the key to identifying those at risk during the early stages of disease diagnosis – or even before the disease starts to develop (1).

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  1. I Laíns et al., “Human plasma metabolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers”, PLoS One, 12, e0177749 (2017). PMID: 28542375.

About the Author

Ruth Steer

Following my journey through academia, I entered the world of scientific writing and never looked back. After several years of working as a medical writer – where I developed a wide range of skills in healthcare publications and communications – I took the opportunity to stretch my creative and journalistic muscles and joined Texere Publishing. Working as Editor on The Ophthalmologist allows me to nurture my skills in scientific writing – and explore the dynamic world of ophthalmology – all within an innovative and exciting company.

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