Disease Area Metabolism & Diabetes

Grappling GK

| Jonathan James

How a new compound promises to selectively activate hepatic glucokinase in a bid to treat type 2 diabetes.

Research Field Drug discovery

The Centryin of Attention

| Jonathan James

A novel protein platform helps neutralize powerful MRSA toxins.

Disease Area Neurological

Breakdown Breakthrough

| Jonathan James

Exploring the link between blood brain barrier permeability and cognitive dysfunction.

Tools & Techniques Informatics

RePURPOSED

| Maryam Mahdi

Recycled and reused: scientists develop a library to help teach old drugs new tricks.

Research Field Cell & gene therapy

Now For the High-Hanging Fruit

| Miguel Forte

We should be thrilled with the success of the approved CD-19 CAR-T therapies. But the field is still young, and we are only scratching the surface.

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Disease Area Cancer

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

Disease Area Neurological

Alzheimer's Awakening

| Jonathan James

Changes in non-REM sleep may indicate early AD

Outside the Lab Policy

Moving on from the Great CRISPR Controversy

| Jonathan James

How will the storm whipped up by He Juinkai’s flagrant disregard for medical ethics affect the wider ambitions of the gene-editing field?

Disease Area Cancer

No-Biotics for Me!

| Gemma North

We don’t fully understand how probiotics affect cancer patient prognosis, so they should be approached with caution – at least for now.

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