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Research Field Cell & gene therapy

Swimming Against the Nucleotides

Rewarding Work

Tomorrow’s cures for retinopathies will likely include advanced gene and cell therapies delivered by precision surgery.

Translational research often requires both scientific and clinical input – and this demands collaboration between groups with complementary skill-sets. Developing gene or cell therapies for retinal disease requires sophisticated expertise in a range of disciplines from molecular biology to microsurgery. Close collaboration was critical for the 2017 approval of a gene therapy for Leber Congenital Amaurosis (LCA), which is a form of childhood blindness that can be caused by the lack of a gene called RPE65. The contribution of our team at UCL/Moorfields was recognized last year, when the 2018 Antonio Champalimaud Vision Award was awarded to the four groups working to develop gene therapy for this condition. Working on a new therapy for an unmet clinical need is its own reward – but it’s certainly an honor to receive such recognition!

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About the Author

James Bainbridge

Professor of Retinal Studies, UCL Institute of Ophthalmology and Moorfields Eye Hospital London.

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