April 2018 Issue of The Translational Scientist

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Articles featured in this issue

Disease Area Diagnostics & prognostics

Variant Database Collaborations – for Cancer and Beyond

| Obi Griffith and Heidi Rehm

It's important to research relevant academic papers, but it's equally important to make sure it's still relevant

Tools & Techniques Omics

Translational Proteomics: Solving the Reproducibility Riddle

| David Chiang

Data analysis in proteomics is not fit for purpose – but here’s how we can get on track

Research Field Neuroscience

VEGF Veteran

| Napoleone Ferrara

Napoleone Ferrara, Distinguished Adjunct Professor of Ophthalmology, UC San Diego School of Medicine, California, USA.

Research Field Cell & gene therapy

The Best Treatment

| Ruth Steer

Is gene therapy the answer to an untreatable form of macular degeneration?

Outside the Lab Analytical science

Faster for Pharma

| Melissa Hanna-Brown

Sitting Down With... Melissa Hanna-Brown, Analytical Technology & Innovation Lead, Pfizer Global R&D, Sandwich, UK.

Outside the Lab Drug discovery

A Problem Shared…

| Roisin McGuigan

It’s time for pharma to join the crowdsourcing revolution.

Disease Area Cancer

Anticipating NRAS Resistance

| William Aryitey

How researchers are unraveling the mystery of melanoma drug resistance

Tools & Techniques Cancer

The Esophageal Balloon

| Sanford Markowitz

The story behind an inflatable pill and a sensitive biomarker that pair up to improve screening for Barrett’s esophagus – and help prevent a highly aggressive cancer

Research Field Drug discovery

Through the Looking Glass

| Niek Buurma

There is a shocking lack of attention given to racemization in drug discovery, despite it having huge implications on the efficacy – and safety – of drugs. We hope the tool we have developed will be the first step towards change.

Other issues of 2018