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Disease Area Neurological

Neurons Under (Astroctyic) Attack

| Jonathan James

Could manipulation of micro-RNA cross-talk between astrocytes and neuronal cells yield a new therapeutic avenue for ALS?

Tools & Techniques Diagnostics & prognostics

Getting to the Heart of the Matter

| Jonathan James

How a combinatorial approach to assessing coronary heart disease could improve diagnosis.

Disease Area Cancer

Two-pronged Attack on Neuroblastoma

| Jonathan James

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.

Tools & Techniques Diagnostics & prognostics

Biomarkers Beyond Our Wildest Dreams

| Luke Turner

Different glycosylation patterns in patients with idiopathic REM sleep behavior disorder could predict the future onset of neurodegenerative disease.

Tools & Techniques Drug delivery

Heavy Metal Wonder

| Jonathan James

An iridium-based photodynamic drug accumulates in cancer cell nuclei – and destroys them from within.

Disease Area Metabolism & Diabetes

Bite-size Breakthroughs: IELS, Imaging and Ocular Cancer

| Jonathan James

The latest advances in translational medicine – condensed into 20-second servings.

Disease Area Cancer

Adaptive Invaders

| Jonathan James

New evidence suggests there’s more to metastasis than MMPs, demanding a therapeutic rethink.

Disease Area Neurological

Breakdown Breakthrough

| Jonathan James

Exploring the link between blood brain barrier permeability and cognitive dysfunction.

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Disease Area Cancer

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

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