Neurons Under (Astrocytic) Attack
Could manipulation of micro-RNA cross-talk between astrocytes and neuronal cells yield a new therapeutic avenue for ALS?
Jonathan James | | Quick Read
Scientists have been aware for more than a decade that astrocytes play a key role in the pathology of amyotrophic lateral sclerosis (ALS). Exactly how they contribute to neuronal death – a key feature of the condition – has remained a mystery. Many have focused on the catalog of molecules that astrocytes produce and exchange with neuronal cells. Now, a paper published in EBioMedicine describes a pathway for this process – at least in ALS patients carrying a specific genetic mutation (1)
Read the full article now
Log in or register to read this article in full and gain access to The Translational Scientist’s entire content archive. It’s FREE and always will be!